Atherosclerosis Essay Example | Topics and Well Written Essays - 1750 words

Atherosclerosis - demonstrate ExampleThe lesions of atherosclerosis start with fatty deposits and gradually develop into complicated lesions. The progressive development of atherosclerotic is classified into six types with increasing effect of compromising the function of the arteries. The first four types of the atherosclerotic lesions do non produce clinical symptoms, while the fourth and fifth type produces clinical symptoms. These clinical symptoms atomic number 18 dependent on the site of compromise of the integrity of the artery.The metabolism of lipids and their serum levels, body fat, obesity, infections and inflammations have a role to play in the development of atherosclerosis and are high risk factors for the development of atherosclerosis. In addition gender, heredity, diseases related to diet like metabolic syndrome, and life style are all factors that can to the development of atherosclerosis by themselves or in conjunction with the other factors.Two mechanisms are relate in the pathophysiology of atherosclerosis consisting of chronic endothelial injury and elevated lipid levels. Risk factors like infection, inflammation, and gage can lead to epithelial injury and elevated lipid levels encourage formation of plaque taut with lipids and initiate the formation of clot or thrombus. The formation of thrombus can lead to a total engine block of the lumen of the artery, which clinically manifests itself in different ways, depending on the location of the blockage, Occlusion in the arteries that supply personal line of credit to the heart manifest as myocardial infarction, while in the case of occlusion in the arteries planning blood to the brain manifests as a stroke or a cerebrovascular event. Infarctions in the liver and kidneys through similar mechanisms impair their functions. The impaired blood flow as a result of the occlusion, if not reversed immediately can lead to ischemia of the involved tissues and death of the tissues,Pharmacologi cal